| 项目编号: | 1407021
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| 项目名称: | DISSERTATION RESEARCH: The maintenance of genetic diversity in captive breeding programs |
| 作者: | James DeWoody
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| 承担单位: | Purdue University
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| 批准年: | 2013
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| 开始日期: | 2014-06-01
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| 结束日期: | 2016-05-31
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| 资助金额: | USD19928
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | genetic diversity
; population
; captive population
; captive breeding program
; further captive breeding program
; captive breeding
; different captive breeding protocol
; biomedical research
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| 英文摘要: | Captive breeding programs have been used to supplement imperiled populations or to re-establish locally extinct populations. Unfortunately, approximately one-third of supplementation and reintroduction attempts are unsuccessful because animals fail to survive and reproduce in the wild. Genetic diversity of a population is a key variable that can influence fitness and, therefore, survival. Because most breeding programs inadvertently select for adaptation to captivity, genetic diversity is often radically altered. To examine the impacts of captive breeding on vertebrate populations, we established six captive populations of white-footed mice and propagated the populations using three breeding schemes typically used in zoos. The existing pedigree will be supplemented with DNA data to form a complete genetic picture of the captive populations.
Through the use of a multi-faceted assessment of genetic diversity via pedigree, marker, and sequence data, this project will compare the evolution of populations bred and maintained in captivity. By utilizing replicate, experimental populations of white-footed mice propagated via different captive breeding protocols, we will also evaluate the efficacy of theoretical approaches to limiting inbreeding, drift, and selection in captive populations. The resulting data will be useful in understanding how different genes and genomic regions evolve, which will be important in further captive breeding programs for recovery of endangered species and for biomedical research. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/96735
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
James DeWoody. DISSERTATION RESEARCH: The maintenance of genetic diversity in captive breeding programs. 2013-01-01.
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