| 项目编号: | 1407006
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| 项目名称: | DISSERTATION RESEARCH: Functional behavioral analysis of positively selected genes in Drosophila |
| 作者: | Rob Kulathinal
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| 承担单位: | Temple University
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| 批准年: | 2013
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| 开始日期: | 2014-06-01
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| 结束日期: | 2017-05-31
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| 资助金额: | USD20254
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | adaptive gene
; genetic basis
; behavioral gene
; gene expression
; genomic analysis
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| 英文摘要: | Behavioral isolation rapidly evolves between species, yet relatively little is known about the genetic basis of pre-mating reproductive isolation, particularly the role of behavioral genes involved in courtship. This knowledge gap is important to fill since behavioral cues are generally species-specific and thought to evolve under strong selective pressures. Using a combination of computational, genetic, and behavioral approaches, the researchers propose to address three main objectives: 1) to identify positively selected genes in the fruit fly, Drosophila melanogaster, that are not specifically expressed in the gonads, 2) to characterize the effects of reducing gene expression in adaptive genes on mating and aggression behavior, and 3) to characterize the adaptive genes involved in behavioral interactions by tissue and molecular function.
The proposed work will extend our understanding of the genetic bases of pre-mating reproductive barriers and their role in early species divergence. Data produced from this proposal will advance the training of students in the areas of genetics, bioinformatics, computational biology, and genomic analysis. Second, this project will implement high school curricula designed to expose students to new high-throughput methods in biology, along with applied hands-on experience using modern genetic and behavioral techniques. Third, the development of a portable high-throughput behavioral lab will be used to increase awareness and engagement in STEM fields to a broader non-scientific audience. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/96768
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Rob Kulathinal. DISSERTATION RESEARCH: Functional behavioral analysis of positively selected genes in Drosophila. 2013-01-01.
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