| 项目编号: | 1355170
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| 项目名称: | The origin and accumulation of hybrid incompatibilities in Tigriopus californicus |
| 作者: | Suzanne Edmands
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| 承担单位: | University of Southern California
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| 批准年: | 2013
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| 开始日期: | 2014-01-01
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| 结束日期: | 2017-12-31
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| 资助金额: | USD554365
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | conflict
; population
; project
; lab-based hybrid population
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| 英文摘要: | Understanding the mechanisms by which new species arise is a fundamental goal of biology. Diverging populations accumulate genetic differences that may cause conflicts (reduced fitness) when populations come back together and hybridize. This leads to further isolation of the populations, and, eventually, to speciation. Speciation work in model systems has concentrated on conflicts involving the gender-determining chromosomes, but a great number of organisms across the tree of life lack these chromosomes. This project uses a copepod, a small marine invertebrate, to understand how genetic conflicts underlying speciation evolve in organisms without gender-determing chromosomes. By hybridizing pairs of populations from a known evolutionary tree, the study will assess how different types of conflicts (nuclear-nuclear vs. nuclear-mitochondrial) accumulate over time and whether the same chromosomal regions evolve conflicts in evolutionarily independent lineages. It will assess the repeatability of evolutionary trajectories by tracking genetic changes in large, lab-based hybrid populations and will identify potential candidate genes involved in conflicts.
This project relates to issues of biodiversity and conservation by exploring how the lack of sex chromosomes impacts species diversification and consequences of hybridization. Its focus on the evolution of nuclear-mitochondrial conflicts, an important cause of disease, gives this study potential biomedical applications. The project will train a postdoctoral researcher, Ph.D. students, and numerous undergraduate researchers. It will also include outreach to diverse communities in and around Los Angeles, including a collaboration with the Aquarium of the Pacific aimed at promoting awareness of the evolutionary processes currently at work in the ocean and their importance. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/97542
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Suzanne Edmands. The origin and accumulation of hybrid incompatibilities in Tigriopus californicus. 2013-01-01.
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