DOI: 10.1111/ele.12656
Scopus记录号: 2-s2.0-84991233676
论文题名: Environmental variability and the evolution of the glucocorticoid receptor (Nr3c1) in African starlings
作者: Hofmeister N.R. ; Rubenstein D.R.
刊名: Ecology letters
ISSN: 14610248
EISSN: 1461-0248
出版年: 2016
卷: 19, 期: 10 起始页码: 1219
结束页码: 1227
语种: 英语
英文关键词: Adaptation
; canalisation
; environmental variability
; fluctuating selection
; stress response
Scopus关键词: glucocorticoid receptor
; adaptation
; animal
; ecosystem
; genetics
; metabolism
; molecular evolution
; Passeriformes
; physiology
; Adaptation, Physiological
; Animals
; Ecosystem
; Evolution, Molecular
; Passeriformes
; Receptors, Glucocorticoid
; Sturnidae
; Vertebrata
英文摘要: One of the primary ways that organisms cope with environmental change is through regulation of the hypothalamo-pituitary-adrenal (HPA) axis, the neuroendocrine system that controls reactions to stress. Variation in genes regulating the HPA axis - particularly the glucocorticoid receptor - may facilitate adaptation to changing climatic conditions by altering expression. Here we examine signatures of selection on the glucocorticoid receptor gene (Nr3c1) in African starlings that inhabit a range of environments, including those with variable climatic conditions. To investigate potential adaptive mechanisms underlying the vertebrate stress response, we sequence the Nr3c1 gene in 27 species of African starlings. Although we find some evidence of positive selection, substitution rate is negatively correlated with variance in precipitation. This suggests climatic cycling in sub-Saharan Africa may have resulted in lower substitution rates to maintain a successful coping strategy. When environmental conditions fluctuate rapidly, variation in the strength of purifying selection can explain evolutionary rate variation. © 2016 John Wiley & Sons Ltd/CNRS. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/107719
Appears in Collections: 气候减缓与适应
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作者单位: Department of Ecology, Evolution and Environmental Biology, Columbia University, 1200 Amsterdam Avenue, New York, NY, 10027, USA. nrh44@cornell.edu; Department of Ecology, Evolution and Environmental Biology, Columbia University, 1200 Amsterdam Avenue, New York, NY, 10027, USA; Center for Integrative Animal Behavior, Columbia University, 1200 Amsterdam Avenue, New York, NY, 10027, USA
Recommended Citation:
Hofmeister N.R.,Rubenstein D.R.. Environmental variability and the evolution of the glucocorticoid receptor (Nr3c1) in African starlings[J]. Ecology letters,2016-01-01,19(10)