Based on the meteorological data and the experimental data of apple at Agro-meteorological Experiment Station of Xifeng which located in the middle part of Loess Plateau, the response characteristics of latest frost and apple growth in spring to climate warming were analyzed. The results showed that the date of latest frost advanced obviously in spring by 3.2 days every ten years. But the variation range of minimum temperature on ground surface in latest frost days became large and the abnormally serious frost disasters happened in a few years. The lasting days of latest forest process showed a periodic increase trend and the negative accumulated minimum temperature on ground surface increased in the abnormal years of 2005 and 2006. The full bloom stage of apple advanced by 5.9 days every ten years since 1984 at P <0.001 probability level, and it advanced even more remarkably after 1998. The full bloom stage during 1998 to 2012 was 10 days earlier than that during 1984 to 1997. Along with the development of climate warming, the advancing rate of full bloom stage was obviously more than that of latest forest date. Therefore, the risk of freezing injury during squaring to full bloom stage of apple was increasing.