In order to study the impact of climate change on winter wheat, by using the wheat growth data and climate data for 19 years in east of Gansu from 1995 to 2013, the physical causation of climate change on winter wheat growth was analyzed with the method of climate inclination rate and correlation analysis. The results showed that: (1)The average temperature in growth period of winter wheat kept rising in 19 years, the climate inclination rate was 0.552℃/10 a. When the effective accumulated temperature increased, the climate inclination rate was 126.1℃/10 a. When the total precipitation increased, the climate inclination rate was 7.619 mm/10 a. When sunshine duration reduced, the climate inclination rate was -42.256/10 a. (2)The dry weigh, growth rate, leaf area, thousand seed weight and climatic yield of winter wheat were increased in 19 years in east of Gansu. (3) Influence of each climate factor on growth of winter wheat was different in each developmental phase. Precipitation in vegetative period played a decisive role in winter wheat growth. Along with the growth of the winter wheat, the influence of precipitation on wheat growth was gradually weakened, but the influence of accumulated temperature and sunshine duration gradually increased. (4)Climatic yield of winter wheat was negatively related to average temperature in the period of duration, but positively related to the precipitation, effective accumulated temperature and sunshine duration.