Astronomical forcing has been shown widely in the Phanerozoic climate change. However, it is still uncertain whether Milankovitch periodicity performed for the much longer Precambrian. In this study, the Mesoproterozoic Xiamaling Formation in the northern North China block was chosen for quantitative lithological cyclic analysis. The section was measured centimeter by centimeter and ranked based on relative depth and redox condition. Spectral analysis of the best-preserved segments revealed statistically significant wavelengths, with ratios comparable to those of theoretical Milankovitch periods for 1 350 Ma. The result was also supported by the isotopic geochronologic data indirectly when the duration of the section was considered. Thus we provide evidence for the existing of orbital periodicity in the Precambrian. The research also supports predictions of Precambrian astronomical parameters from theoretical calculations. It contributes new knowledge on the Earth's faster rotation rate, orbital dynamics, climate change as well as deep-time cyclostratigraphic study in the further remote Precambrian.