The dynamic changing features of Xilinguole League desertified land were analyzed by selecting the Landsat satellite images of 1975-2014. The results showed that the desertification of Xilinguole League underwent a gradual transition from non-to severe desertification from east to west, the total desertification area increased first and decreased later, and reached the maximum in 2005. The changes in desertification occurred basically according to the contemporaneous climate changes. The overall changes in desertification were small before 1985 and dramatic changes occurred after 1985 with different situations from region to region, the increase and decrease of the light desertified land area had direct impact on the changes in the total area of desertification. The centroids of the three degrees, i.e. heavy, moderate and light, of desertified lands were in the order from southwest to northeast. The centroid of desertification had a sustained movement to the east before 2005 and then moved westward.