Background Several prospective studies have been conducted to examine the relationship between fruit juice intake and risk of incident type 2 diabetes, but results have been mixed. In the present study, we aimed to estimate the association between fruit juice intake and risk of type 2 diabetes. Methods PubMed and Embase databases were searched up to December 2013. All prospective cohort studies of fruit juice intake with risk of type 2 diabetes were included. The pooled relative risks (RRs) with 95% confidence intervals (CIs) for highest vs. lowest category of fruit juice intake were estimated using a random-effects model. Results A total of four studies (191,686 participants, including 12,375 with type 2 diabetes) investigated the association between sugar-sweetened fruit juice and risk of incident type 2 diabetes, and four studies (137,663 participants and 4,906 cases) investigated the association between 100% fruit juice and risk of incident type 2 diabetes. A higher intake of sugar-sweetened fruit juice was significantly associated with risk of type 2 diabetes (RR = 1.28, 95%CI = 1.04–1.59, p = 0.02), while intake of 100% fruit juice was not associated with risk of developing type 2 diabetes (RR = 1.03, 95% CI = 0.91–1.18, p = 0.62). Conclusions Our findings support dietary recommendations to limit sugar-sweetened beverages, such as fruit juice with added sugar, to prevent the development of type 2 diabetes.
Department of Maternal and Child Health, School of Public Health, Shandong University, Jinan, China;Department of Maternal and Child Health, School of Public Health, Shandong University, Jinan, China;Department of Maternal and Child Health, School of Public Health, Shandong University, Jinan, China;Department of Maternal and Child Health, School of Public Health, Shandong University, Jinan, China;Department of Maternal and Child Health, School of Public Health, Shandong University, Jinan, China;Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan, China;Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, United States of America;Department of Endocrinology, Linyi People's Hospital, Linyi, China;Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, United States of America
Recommended Citation:
Bo Xi,Shuangshuang Li,Zhaolu Liu,et al. Intake of Fruit Juice and Incidence of Type 2 Diabetes: A Systematic Review and Meta-Analysis[J]. PLOS ONE,2014-01-01,9(3)