DOI: 10.1016/j.atmosenv.2014.02.036
Scopus记录号: 2-s2.0-84895963978
论文题名: Different toxic mechanisms are activated by emission PM depending on combustion efficiency
作者: Uski O ; , Jalava P ; I ; , Happo M ; S ; , Leskinen J ; , Sippula O ; , Tissari J ; , Mäki-Paakkanen J ; , Jokiniemi J ; , Hirvonen M ; -R
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2014
卷: 89 起始页码: 623
结束页码: 632
语种: 英语
英文关键词: Biomass combustion
; Chemical composition
; Combustion particles
; Health effects of aerosols
Scopus关键词: Biomass
; Cell culture
; Health
; Macrophages
; Metabolism
; Particulate emissions
; Polycyclic aromatic hydrocarbons
; Biomass combustion
; Chemical compositions
; Fine and ultrafine particles
; Health effects
; Polycyclic aromatic hydrocarbon (PAH)
; Proinflammatory response
; Residential wood combustions
; Toxicological properties
; Combustion
; aerosol
; ambient air
; biomass burning
; chemical composition
; combustion
; genotoxicity
; health impact
; morbidity
; mortality
; PAH
; soot
; toxic material
; toxicology
; traffic emission
; ambient air
; animal cell
; article
; cell cycle
; combustion
; comet assay
; comparative study
; controlled study
; DNA damage
; G2 phase cell cycle checkpoint
; macrophage
; mouse
; nonhuman
; oxidative stress
; particulate matter
; priority journal
; reactor
; wood
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Ambient air levels of fine particulate matter (PM≤2.5μm) are associated with mortality and morbidity. In addition to traffic, large quantities of fine and ultrafine particles (UFPs≤100nm) are emitted by residential wood combustion. Polycyclic aromatic hydrocarbon (PAH) and soot-rich emissions from small scale heating appliances have been linked with a plethora of toxicological effects. Recently, new technology appliances have been introduced into use although there are several uncertainties related to the toxicological properties of those emissions. In this study, PM1 (PM≤1μm) emissions from three different biomass combustion situations were compared. PM samples were produced in a novel adjustable biomass combustion reactor to avoid the problems encountered if one uses different appliances to generate the desired combustion conditions. The combustion conditions represented efficient, intermediate and smoldering situations. The concentration related effects of the particles (15, 50,150 and 300μgml-1) were investigated in a RAW264.7 macrophage cell line after 24h' exposure. We analyzed cellular metabolic activity, cell cycle, and indicators of genotoxicty, oxidative stress and proinflammatory responses. Interestingly, the particles collected from smoldering and intermediate combustion conditions decreased cellular metabolic activity less than those from efficient combustion (10-fold difference). However, the samples from intermediate and smoldering combustion evoked greater DNA damage in the comet assay (2.5-fold difference). In contrast, only the particulate samples from efficient combustion triggered G2-cell cycle arrest and oxidative stress in the macrophages. These results indicate that ash rich PM emissions from appliances with almost complete combustion may still exert health impacts. However, particulate emissions from efficient combustion were small when compared to the two other situations. Thus, even with their faults and the obvious need for development, consumers should be encouraged to purchase efficient combustion devices in order to reduce exposure to PM induced adverse health effects. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/81120
Appears in Collections: 气候变化事实与影响
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作者单位: University of Eastern Finland, Department of Environmental Science, P.O. Box 1627, FI-70211 Kuopio, Finland; National Institute for Health and Welfare, Department of Environmental Health, P.O. Box 95, FI-70701 Kuopio, Finland; VTT Technical Research Centre of Finland, P.O. Box 1000, FI-02044 VTT, Espoo, Finland
Recommended Citation:
Uski O,, Jalava P,I,et al. Different toxic mechanisms are activated by emission PM depending on combustion efficiency[J]. Atmospheric Environment,2014-01-01,89